The pap operon of avian pathogenic Escherichia coli strain O1:K1 is located on a novel pathogenicity island.

نویسندگان

  • Subhashinie Kariyawasam
  • Timothy J Johnson
  • Lisa K Nolan
چکیده

We have identified a 56-kb pathogenicity island (PAI) in avian pathogenic Escherichia coli strain O1:K1 (APEC-O1). This PAI, termed PAI I(APEC-O1), is integrated adjacent to the 3' end of the pheV tRNA gene. It carries putative virulence genes of APEC (pap operon), other E. coli genes (tia and ireA), and a 1.5-kb region unique to APEC-O1. The kps gene cluster required for the biosynthesis of polysialic acid capsule was mapped to a location immediately downstream of this PAI.

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عنوان ژورنال:
  • Infection and immunity

دوره 74 1  شماره 

صفحات  -

تاریخ انتشار 2006